Citizen-centered, auditable and privacy-preserving population genomics

نویسندگان

چکیده

The growing number of health-data breaches, the use genomic databases for law enforcement purposes and lack transparency personal genomics companies are raising unprecedented privacy concerns. To enable a secure exploration datasets with controlled transparent data access, we propose citizen-centric approach that combines cryptographic privacy-preserving technologies, such as homomorphic encryption multi-party computation, auditability blockchains. Our open-source implementation supports queries on encrypted hundreds thousands individuals, minimal overhead. We show real-world adoption our system alleviates widespread concerns encourages access sharing researchers. Sharing raises due to sensitive nature data. A involving technologies blockchains is proposed address this problem.

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ژورنال

عنوان ژورنال: Nature Computational Science

سال: 2021

ISSN: ['2662-8457']

DOI: https://doi.org/10.1038/s43588-021-00044-9